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Can Adults Grow New Neurons? What Neuroscience Means for Your Recovery

  • mcvarela0
  • 2 hours ago
  • 3 min read

For a long time, the scientific consensus was clear: you are born with a fixed number of neurons, and once they are gone, they are gone. The brain, we were told, was essentially hardwired by adulthood with little capacity for change. The good news, backed by decades of growing research, is that this is no longer the whole story.


As physiotherapists, this science matters deeply to us, because understanding how the brain adapts and regenerates changes the way we approach pain, rehabilitation, and long-term recovery.


The Science of Neurogenesis


Neurogenesis, the process by which new neurons are formed, was once thought to occur only during foetal development. However, research has since confirmed that neurogenesis does occur in the adult brain, most notably in the hippocampus, the region responsible for memory, learning, and emotional regulation, and in the olfactory bulb.


In 2026, the neuroscience community continues to build on this understanding. While the extent and clinical implications of adult neurogenesis are still being explored, what is increasingly clear is that the brain retains a remarkable capacity for plasticity throughout life. It can reorganise, adapt, strengthen connections, and in certain regions, generate new cells. This is known as neuroplasticity, and it is one of the most exciting areas of science relevant to physiotherapy today.


What Promotes Neurogenesis?


This is where it gets particularly interesting for those of us working in rehabilitation and physical health. The factors that most consistently promote neurogenesis and neuroplasticity in adults are the same things we recommend to our patients every single day.


Aerobic exercise is consistently shown to be one of the most powerful stimulators of brain derived neurotrophic factor, known as BDNF, a protein that supports the survival and growth of neurons. Even moderate regular movement, brisk walking, cycling, or swimming, can have measurable effects on brain health and cognitive resilience.


Quality sleep, as we have explored before, is when the brain consolidates learning and clears metabolic waste through the glymphatic system. Chronic sleep deprivation actively impairs neuroplasticity. Stress reduction, social connection, learning new skills, and a diet rich in omega-3 fatty acids and antioxidants all contribute positively as well.


What This Means for Pain and Recovery


From a physiotherapy perspective, neuroplasticity is central to how we understand and treat chronic pain. Pain is not simply a signal from damaged tissue. It is a complex output of the nervous system, shaped by experience, belief, emotion, and context. A sensitised nervous system can produce pain long after tissues have healed.


The encouraging truth is that just as the nervous system can become sensitised, it can also be recalibrated. Through graded movement, pain education, and consistent rehabilitation, we can help retrain the brain's response to pain signals. Patients who understand this often make faster and more sustained progress.


You Can Change Your Brain


The old idea that the adult brain is fixed and immovable is outdated. You have more capacity for change, recovery, and growth than you may have been told. And the tools that support that change, movement, sleep, connection, and learning, are all within reach.


At Smartphysio, we integrate the latest neuroscience into everything we do. Call us now on 020 7435 4910 or visit www.smartphysio.co.uk to book your assessment today. Your brain, and your body, are more adaptable than you think.



 
 

About Our Expert

Sammy Margo, Chartered Physiotherapist and Founder of SmartPhysio

Sammy Margo

​Founder and Director of Physiotherapy Services
Chartered Physiotherapist
MSc, MMACP, AACP, MCSP, HCPC

 

Sammy Margo is a Chartered Physiotherapist with over 30 years’ clinical experience. She has worked across the NHS, professional sport, and private practice, and was England’s first female physiotherapist to work in professional football.

Her areas of clinical expertise include:

  • Senior care and complex rehabilitation

  • Home visit and community-based physiotherapy

  • Sleep, recovery, and performance

  • Musculoskeletal and neurological rehabilitation


Sammy is a recognised sleep expert, a former spokesperson for the Chartered Society of Physiotherapy, and a regular contributor to national media including The Telegraph, The Guardian, Daily Mail, and Stylist. She is the author of The Good Sleep Guide.

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